The freeze-drying machine consists of a refrigeration system, a vacuum system, a heating system, and an electrical instrumentation control system. The main components are drying ovens, condensers, refrigeration units, vacuum pumps, heating/cooling devices, etc. Freeze-drying (hereinafter referred to as lyophilization) is a method in which a water-containing substance is first frozen into a solid state, and then the moisture therein is sublimated from a solid state to a gaseous state to remove the water and preserve the substance.

Freeze Dryer Principles and Advantages Features Freeze Dryer Principles and Advantages We know that the freeze-dried freeze-drying principle is: Freeze-drying is a technique that uses the principle of sublimation to dry a substance that freezes the dried substance at a low temperature. Then, in a proper vacuum environment, the frozen water molecules are directly sublimated into a process in which water vapor escapes. The product obtained by lyophilization is called a lyophilizer. This process is called lyophilization. Before the material is dried, it is always at a low temperature (frozen state). At the same time, ice crystals are evenly distributed in the material. The sublimation process does not occur due to dehydration and avoids side effects such as bubbles and oxidation caused by water vapor. The dry substance is in the form of a dry sponge, which is basically unchanged in volume, easily soluble in water and restored to its original state. To prevent physicochemical and biological degeneration of dry matter to a maximum extent.

What are the benefits of freeze drying? Let's take a look at:

one. Freeze-drying is performed at a low temperature and is therefore particularly suitable for many heat-sensitive materials. If proteins, microorganisms and the like do not degenerate or lose their vitality. Therefore, it has been widely used in medicine.

two. Since the drying is carried out in a frozen state, the volume almost does not change and the original structure is not condensed.

three. After drying, the porous material is loose and porous, and it dissolves rapidly after adding water, and it quickly and completely recovers its original properties almost immediately.

four. Oxidation-promoting substances are protected because the drying is performed under vacuum with little oxygen.

Fives. The loss of some of the volatile components in the material when dried at low temperatures is small enough for some chemical products and foods to dry.

six. In the process of freeze-drying, the growth of microorganisms and the role of enzymes cannot be performed and thus the original costume can be maintained.

Seven. Drying can eliminate more than 95-99% of water so that the dried product can be stored without deterioration.

Therefore, the freeze-drying of freeze dryers is currently widely used in scientific research and other sectors of the food industry of the pharmaceutical industry.

Application Field of Freeze Dryer Freeze drying is a method of pre-freezing an aqueous material and then sublimating it under vacuum to obtain a dried product. The freeze-dried articles have basically the same biological and chemical properties, are easy to preserve for a long time, can return to their pre-lyophilized form after adding water, and can maintain their original biochemical characteristics. Therefore, freeze-drying technology has been widely used in the chemical industry, biological products and other fields.

Before freeze-drying using a lyophilizer, the items to be dried are placed in a low-temperature refrigerator or liquid nitrogen so that the items are completely frozen in ice for freeze-drying.

The lyophilization machine is connected to the vacuum pump by a vacuum tube, and the connection uses international standard clamps. The clamp contains a seal rubber ring. Before connecting, apply a proper amount of vacuum grease to the rubber ring, and then tighten the clamp.

The power socket of the vacuum pump is located on the right side of the main unit, and the power cord of the vacuum pump is connected.

Check the vacuum pump and confirm that the vacuum pump oil has been filled. Do not run without oil. The oil level must not be lower than the midline of the oil mirror. Before the first use, please read the vacuum pump instruction manual.

The O-ring seal rubber ring above the host cold trap should be kept clean. When it is used for the first time, a thin layer of vacuum grease can be applied. The plexiglass cover is placed on the rubber ring and gently rotated for several times to facilitate sealing. .

Lyophilizers have a wide range of applications in the pharmaceutical, biological products, chemical and food industries. For heat-sensitive substances such as antibiotics, vaccines, blood products, enzyme hormones and other biological tissues, freeze-drying technology is very suitable.